Vol. 1, Issue 1, Part A (2024)

Ayurveda, the traditional Indian system of medicine, has long utilized polyherbal formulations as an essential therapeutic strategy. These formulations combine multiple herbs to enhance efficacy, reduce toxicity, and target various aspects of disease pathology simultaneously. Contemporary phytotherapy, rooted in scientific validation of plant-based treatments, increasingly recognizes the value of such synergistic herbal blends. This paper reviews the foundational principles of polyherbalism in Ayurveda, examines the pharmacodynamic rationale behind combining herbs, and evaluates current scientific evidence supporting their efficacy in the treatment of various chronic and lifestyle diseases. Furthermore, it addresses the challenges in standardization, quality control, and clinical validation of polyherbal formulations while suggesting integrative frameworks to bridge traditional wisdom and modern medicine.